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R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI) with potential antineoplastic activity
EW-7197 inhibits breast cancer metastasis to the lung
55(22):9416-33
SB-431542 was intraperitoneally dosed to mice at 10 mg/kg once per day
LDN-27219 tebradine R547 is orally bioavailable diaminopyrimidineLDN 27219 is a reversible Transglutaminase 2 (TG2) inhibitor that binds at the GTPase site. Product information CAS Number: 312946 37 5 Molecular Weight: 408. 50 Formula: C20H16N4O2S2 Synonym: LDN 27219 Chemical Name: 2 ({4 oxo 3,5 diphenyl 3H,4H thieno[2,3 d]pyrimidin 2 yl}sulfanyl)acetohydrazide Smiles: NNC(=O)CSC1=NC2SC=C(C=2C(=O)N1C1C=CC=CC=1)C1C=CC=CC=1 InChiKey: WLBUICQBNZXIDJ UHFFFAOYSA N InChi: InChI=1S C20H16N4O2S2 c21 23 16(25)12 28 20 22 18
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