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CP-465022 (maleate) hrin-β and ATR in vitro

SKU: 24042351235

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Description

and ATR in vitro

InChi: InChI=1S/C65H101N15O25/c1-10-31(7)51(80-61(100)39(23-29(3)4)73-59(98)41(26-45(68)83)75-56(95)37(18-21-46(84)85)70-53(92)33(9)69-54(93)35(66)25-48(88)89)63(102)76-42(27-49(90)91)60(99)77-43(28-81)62(101)74-40(24-34-15-13-12-14-16-34)58(97)72-36(17-20-44(67)82)55(94)71-38(19-22-47(86)87)57(96)79-52(32(8)11-2)64(103)78-50(30(5)6)65(104)105/h12-16

crystal violet

SP600125 kills p53-deficient cells more efficiently than their p53-proficient counterparts

CP-465022 (maleate) hrin-β and ATR in vitroIC50: 25 nM for AMPA receptor mediated currents in rat cortical neurons CP 465022 is an AMPA antagonist. The inhibition of alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid (AMPA) receptor has been hypothesized to lead to neuroprotective efficacy after cerebral ischemia on the basis of the activity in ischemia models of a variety of compounds with varying selectivity for AMPA over other glutamate receptor subtypes. In vitro: CP 465022 inhibited

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