Human IL11 Nucleic Acid Separation which regulates progression through the

which regulates progression through the cell cycle

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Human IL11 Nucleic Acid Separation which regulates progression through theBcakground Interleukin 11 (IL 11) is a pleiotropic cytokine in the IL 6 family, which also includes LIF, CNTF, Oncostatin M, Cardiotrophin 1, IL 27 and IL 31 (1 3). In humans, IL 11 was also independently discovered as an adipogenesis inhibitory factor (AGIF) (3). The human IL 11 cDNA encodes a 199 amino acid (aa) precursor, which generates a 178 aa, 19 kDa mature unglycosylated protein. Mature human IL 11 shares 88%, 88%, and 96% aa sequence identity