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and cytoplasmic
This product was previously listed under catalog number 15-86000 and is now updated to BF-99526610 for improved product management
This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins
whose members function as regulators of the cell cycle
Human TROP2 Cell Lines & Culture Kits and cytoplasmicTROP 2 is a cell surface glycoprotein highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors. The human TROP 2 protein is composed of a putative 26 amino acid (aa) signal sequence, a 248 aa extracellular domain, a 23 aa transmembrane region and a 26 aa cytoplasmic domain. It is able to transduce an intracellular calcium signal with adhesive functions and probably plays a role in tumor
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