Recombinant Human GM-CSF (CSF2) Cell Biologics Size:50 µg (International) Ligation of membrane-associated IL-15/IL-15 R

Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells (11)

The protein encoded by this gene contains a caspase recruitment domain (CARD)

This product was previously listed under catalog number 15-38230 and is now updated to BF-63176890 for improved product management

A mutation in this gene may be associated with adult myoclonic epilepsy

Recombinant Human GM-CSF (CSF2) Cell Biologics Size:50 µg (International) Ligation of membrane-associated IL-15/IL-15 RDescription GM CSF is a hematopoietic growth factor that is produced by endothelial cells, monocytes, fibroblasts and T lymphocytes following their activation by antigens or mitogens. GM CSF stimulates the development of macrophages and neutrophils and plays a role in the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. Approximately 90% of the secreted colony stimulating activities are due to GM CSF.