EHT 1610 Size:Contact [email protected] for quotation 3R)-2-[[(2S)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]acetic acid

3R)-2-[[(2S)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]acetic acid

is a potent proteasome inhibitor (PI) with potential antineoplastic activity

It also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase

InChiKey: RLCLASQCAPXVLM-NSHDSACASA-N

EHT 1610 Size:Contact [email protected] for quotation 3R)-2-[[(2S)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]acetic acidEHT 1610 is a strong inhibitor of DYRKs family kinases, with IC50s of 0. 36, 0. 59 nM for DYRK1A and DYRK1B, respectively. Product information CAS Number: 1425945 60 3 Molecular Weight: 383. 40 Formula: C18H14FN5O2S Chemical Name: methyl 9 [(2 fluoro 4 methoxyphenyl)amino] [1,3]thiazolo[5,4 f]quinazoline 2 carboximidate Smiles: COC1C=C(F)C(=CC=1)NC1N=CN=C2C=CC3N=C(SC=3C2=1)C(=N)OC InChiKey: RYBNARZBIXTFJS UHFFFAOYSA N InChi: InChI=1S C18H14FN5O2S c1