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136(3):1038-48
Formula: C20H20N6S4
inhibits DNA-binding activity of NFκB (p ≤ 0
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα)
BW 246C 637CT018159 136(3):1038-48BW 246C is a DP receptor agonist. The prostaglandin D2 (PGD2) receptors, members of G protein coupled receptors, bind and are activated by prostaglandin D2. PGD2 receptors include the following proteins prostaglandin D2 receptor 1 (DP1) and prostaglandin D2 receptor 2 (DP2). In vitro: BW 246C was found to be the less active C 8 diastereomer of the DP receptor agonist its analog BW 245C, having 70 fold less activity than that of BW 245C. For BW 245C, a
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