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"rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor
InChi: InChI=1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4
Both c-Kit and VEGFR2 are overexpressed in a variety of cancers
Formula: C30H31FN2O
BMX-IN-1 - CAS# 1431525-23-3 Size:Solid 10 mg "rule of 5" compliant andBMX IN 1 is a selective irreversible BMX inhibitor for prostate cancer. BMX IN 1 can covalently modifies Cys496. BMX IN 1 inhibits the proliferation of Tel BMX transformed Ba F3 cells at two digit nanomolar concentrations but requires single digit micromolar concentrations to inhibit the proliferation of prostate cancer cell lines. MK2206, is able to potentiate BMX inhibitor's antiproliferation efficacy against prostate cancer cells. Product