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Lenalidomide-acetylene-C5-COOH 196moxiterol Chemical Name: tert-butyl 4-[(adamantan-1-yl)amino]-3-{[(pyrimidin-5-yl)methylidene]amino}benzoate

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Description

Chemical Name: tert-butyl 4-[(adamantan-1-yl)amino]-3-{[(pyrimidin-5-yl)methylidene]amino}benzoate

Cell cycle analysis of H295R cells after 24 h of G-1 treatment demonstrates a cell cycle arrest in the G2 phase

Tauroursodeoxycholate reduces Angiotensin (Ang) II induced abdominal aortic aneurysm (AAA) formation in ApoE-/- mice

Selitrectinib (LOXO-195) achieves low nanomolar inhibitory activity against TRKA G595R

Lenalidomide-acetylene-C5-COOH 196moxiterol Chemical Name: tert-butyl 4-[(adamantan-1-yl)amino]-3-{[(pyrimidin-5-yl)methylidene]amino}benzoateLenalidomide acetylene C5 COOH (compound 43; Cereblon ligand linker Conjugate) is the Lenalidomide based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide acetylene C5 COOH can be connected to the ligand for protein by a linker to form PROTAC. Product information CAS Number: 2429878 72 6 Molecular Weight: 382. 41 Formula: C21H22N2O5 Chemical Name: 8 [2 (2,6 dioxopiperidin 3 yl) 1 oxo 2,3 dihydro 1H isoindol 4 yl]oct 7 ynoic acid

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