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Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
InChiKey: VFHGCZZAGNKHIX-UHFFFAOYSA-N
InChi: InChI=1S/C18H19F3N2O4S2/c19-18(20
InChiKey: FWYSBEAFFPBAQU-LBPRGKRZSA-N
A-582941 dihydrochloride llin II Inhibition of Dihydroorotate Dehydrogenase OvercomesA 582941 dihydrochloride is a potent, selective and brain penetrant partial agonist of 7 nAChR, with Kis of 10. 8 and 16. 7 nM in rat brain membranes and human frontal cortex, respectively. A 582941 dihydrochloride also binds to human 5 HT3 receptor with a Ki of 150 nM. A 582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research. Product information CAS Number: 848591 90 2 Molecular