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AZD-2461 cuases resistance and high P-gp expression levels in BRCA2-deficient mouse breast cancer line KB2P3
P S Wollert
InChiKey: MJRWWLRDMAXCFR-UHFFFAOYSA-N
Smiles: C[N+](C)(C)CCOP([O-])(=O)OC[C@@H](COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC
IRAK4-IN-6 - CAS# 2454244-02-9 nanthrene AZD-2461 cuases resistance and highIRAK4 IN 6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma. Product information CAS Number: 2454244 02 9 Molecular Weight: 504. 59 Formula: C25H32N10O2 Chemical Name: methyl 4 [(1r,4r) 4 {[6 (cyanomethyl) 2 [(1 methyl 1H pyrazol 4 yl)amino]pyrido[3,2 d]pyrimidin 4 yl]amino}cyclohexyl]piperazine 1 carboxylate Smiles:
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