EN6 HIBO 1]octane-3-carboxylic acid

1]octane-3-carboxylic acid

but shows no obvious effect on inositol phosphate-1 formation induced by BK (3 nM) activation of B2 receptor in human fibroblast MRC5

Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs)

Meys which possesses anti-cancer activity

EN6 HIBO 1]octane-3-carboxylic acidEN6 is a small molecule in vivo activator of autophagy that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal the vacuolar H+ ATPase (v ATPase). EN6 mediated ATP6V1A modification decouples the v ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy. EN6 clears TDP 43 aggregates, a causative agent in frontotemporal dementia, in a lysosome dependent manner.