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T it was approved in Feb 2008 by European Medicines Agency for use within the EU and is listed on the Australian PBS with certain restrictions
DUN09716 (0-100 μM) shows strong inhibition selectivity in NSCLC cells with IC50s ranging from 39
5-trifluoropentanamide
PS48 was used at 5 µM concentration in cell culture
DM3 - CAS# 796073-54-6 e D6 Hydrochloride T it was approved inDM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody drug conjugates (ADCs). Product information CAS Number: 796073 54 6 Molecular Weight: 766. 34 Formula: C37H52ClN3O10S Synonym: Maytansinoid DM3 Chemical Name: (1S, 2R, 3S, 5S, 6S, 20R, 21S) 11 chloro 21 hydroxy 12, 20 dimethoxy 2, 5, 9, 16 tetramethyl 8, 23 dioxo 4, 24 dioxa 9, 22 diazatetracyclo[19. 3. 1. 1, .
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