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which inhibited locus coeruleus (LC) cell firing with EC50 value of 2
detailed information refer to WO 2012158957 A2 and WO 2007013896
Sparsentan causes a significant lowering of blood pressure at the lowest dose tested (10 µmol/kg/day) in spontaneously hypertensive rats
Int Arch Allergy Immunol
CHMFL-ABL-121 Catalog No.:M27849-C which inhibited locus coeruleus (LC)CHMFL ABL 121 is a highly potent type II ABL kinase inhibitor with IC50s of 2 nM and 0. 2 nM against purified inactive ABL wt and T315I kinase protein, respectively. Product information CAS Number: 2270879 07 5 Molecular Weight: 580. 67 Formula: C30H31F3N6OS Chemical Name: N {4 [(4 methylpiperazin 1 yl)methyl] 3 (trifluoromethyl)phenyl} 3 ({3 [(E) 2 (pyridin 2 yl)ethenyl] 1H indazol 6 yl}sulfanyl)propanamide Smiles:
US$ 441.00
US$ 308.00