RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 Chemical Name: 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol

Chemical Name: 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol

7-Epidocetaxel

CAS Number: 1380548-02-6

InChi: InChI=1S/C20H25N7O6

RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 Chemical Name: 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenolRX 3117, also known as TV 1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX 3117 is taken up by cells through a carrier mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX DP) and triphosphate forms (RX TP). The triphosphate form is incorporated into