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SB-334867 (100 pM– 10 μM) inhibits the orexin-A (10 nM) and orexin-B (100 nM)-induced calcium responses in a concentration-dependent manner
CAS Number: 1285515-21-0
is a calcium channel blocker
with Kds of 1
ABT-724 trihydrochloride Size:Contact [email protected] for quotation SB-334867 (100 pM– 10 μM)ABT 724 trihydrochloride is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12. 4 nM for human dopamine D4 receptor. ABT 724 trihydrochloride is a potent partial agonist at the rat D4 (EC50 of 14. 3 nM) and the ferret D4 receptor (EC50 of 23. 2 nM), and has no effect on dopamine D1, D2, D3, or D5 receptors. ABT 724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side effect
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