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8aS)-3a-[(3aS
17-dimethoxy-21-[2-(methylamino)ethyl]-5
inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage
being unable to significantly reduce relapses into MS among patients beyond a placebo
LDN-193189 HCl Size:Contact [email protected] for quotation 8aS)-3a-[(3aSLDN 193189 is a highly potent small molecule BMP inhibitor with IC50 of 5 and 30 nM for ALK2 and ALK3, respectively. LDN193189 also inhibits BMP type I receptors ALK6 (TGF1 BMP signaling) and subsequent SMAD phosphorylation. Product information CAS Number: 1435934 00 1 Molecular Weight: 479. 40 Formula: C25H24Cl2N6 Chemical Name: 4 (6 (4 (piperazin 1 yl)phenyl)pyrazolo[1, 5 a]pyrimidin 3 yl)quinoline dihydrochloride Smiles: Cl. Cl.
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