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CX-5461 dihydrochloride Catalog No.:M14526-2 26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H

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Description

26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H

significantly inhibits the ability of trichomonads to secrete LTB4 compared to results for trichomonads treated with medium

CAS Number: 1011301-27-1

InChiKey: HHUNWLYVWGUPOT-FLAQYFRFSA-H

CX-5461 dihydrochloride Catalog No.:M14526-2 26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11HCX 5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I mediated rRNA synthesis, with IC50s of 142 nM in HCT 116, 113 nM in A375, and 54 nM in MIA PaCa 2 cells, and shows little or no effect on Pol II (IC50 25 M). Product information Molecular Weight: 586. 54 Formula: C27H29Cl2N7O2S Chemical Name: 4 (4 methyl 1,4 diazepan 1 yl) N [(5 methylpyrazin 2 yl)methyl] 8 oxo 11 thia 1,3 diazatetracyclo[8. 7. 0. 0,. 0,]heptadeca

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