Tandospirone - CAS# 87760-53-0 Catalog No.:M10386-10 ⁷]pentadeca-1(11)

⁷]pentadeca-1(11)

and activation and/or production of nuclear factor-κB

and a second study published later that same year reported that a PAC-1 derivative (called S-PAC-1) was well tolerated in a small Phase I Clinical Trial of pet dogs with lymphoma

Formula: C15H13F6N3O4S2

Tandospirone - CAS# 87760-53-0 Catalog No.:M10386-10 ⁷]pentadeca-1(11)Tandospirone citrate is a potent and selective 5 HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR 2, SR 1C, 1, 2, D1 and D2 receptors (Ki values ranging from 1300 41000 nM). IC50 Value: 275 nM(Ki) Target: 5 HT1Ain vitro: Tandospirone is most potent at the 5 HT1A receptor, displaying a Ki value of 27 + 5 nM. The agent is approximately two to three orders of magnitude less potent at 5 HT2, 5 HT1C, alpha 1 adrenergic, alpha 2