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BSEP induction above vehicle (DMSO) control is observed at concentrations as low as 1 nM
Chemical Name: 2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H
GW788388 (50 mg/kg/day
has a long half-life and tissue penetration
Epidermal Growth Factor Receptor Peptide (985-996) Catalog No.:M23036-C BSEP induction above vehicle (DMSO)EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by the binding of its specific ligands, including epidermal growth factor and transforming growth factor . EGFR dimerization stimulates its intrinsic intracellular protein tyrosine kinase activity. As a result, autophosphorylation of several tyrosine (Y) residues on the C terminal domain of EGFR occurs. These include Y992, Y1045, Y1068, Y1148 and Y1173. This
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