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IACS-9571 - CAS# 1800477-30-8 size:10mg solid 31)32)19-37-14-12-36(2)13-15-37/h3-7

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Description

31)32)19-37-14-12-36(2)13-15-37/h3-7

InChi: InChI=1S/C21H17N3O2S/c1-14-11-16(15(2)23(14)18-9-6-10-22-13-18)12-19-20(25)24(21(26)27-19)17-7-4-3-5-8-17/h3-13H

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo

Chemical Name: 1-Methyl-7-nitro-2H-3

IACS-9571 - CAS# 1800477-30-8 size:10mg solid 31)32)19-37-14-12-36(2)13-15-37/h3-7IACS 9571, CAS No. 1800477 30 8, is a potent and selective inhibitor TRIM24 and BRPF1. IACS 9571 has low nanomolar affinities for TRIM24 and BRPF1 (ITC Kd = 31 nM and 14 nM, respectively). With its excellent cellular potency (EC50 = 50 nM) and favorable pharmacokinetic properties (F = 29%), IACS 9571 is a high quality chemical probe for the evaluation of TRIM24 and or BRPF1 bromodomain function in vitro and in vivo. Product information CAS Number:

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