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20)21)23-17(24-16)22-14-5-3-2-4-6-14
Smiles: [2H]C([2H])([2H])C(O)(C1N=C(CCC)N(CC2C=CC(=CC=2)C2=CC=CC=C2C2=NNN=N2)C=1C(O)=O)C([2H])([2H])[2H]
It is a good chemical tool to enable interrogation of GPR39 signaling in different cellular contexts
with an IC50 of 38 nM for hLPA5
Dovitinib-D8 zine-d3 20)21)23-17(24-16)22-14-5-3-2-4-6-14Dovitinib D8 (CHIR 258 D8) is the deuterium labeled Dovitinib. Dovitinib (CHIR 258) is a multi targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8 9, 10 13 8, 27 210 nM for FLT3, c Kit, FGFR1 FGFR3, VEGFR1 VEGFR2 VEGFR3 and PDGFR PDGFR, respectively. Product information CAS Number: 1246819 84 0 Molecular Weight: 400. 48 Formula: C21H21FN6O Chemical Name: 4 amino 5 fluoro 3 {6 [4 methyl(2,2,3,3,5,5,6,6 H)piperazin 1 yl] 1H 1,3 benzodiazol 2 yl}