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second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity
Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin
CAS Number: 87333-19-5
InChi: InChI=1S/C27H27N7O2S/c1-17-14-29-18(15-28-17)16-30-26(36)23-24(35)19-8-9-22(33-11-5-10-32(2)12-13-33)31-25(19)34-20-6-3-4-7-21(20)37-27(23)34/h3-4
PF-06700841 P-Tosylate Size:Contact [email protected] for quotation second-generation small-molecule inhibitor of thePF 06700841 P Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. PF 06700841 P Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6. 49 M, respectively. Product information CAS Number: 2140301 96 6 Molecular Weight: 561. 60 Formula: C25H29F2N7O4S Chemical Name: 4 methylbenzene 1 sulfonic acid; 4 {8 [(1S) 2,2 difluorocyclopropanecarbonyl] 3,8 diazabicyclo[3. 2. 1]octan 3 yl} N (1
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