DM4 TAC SGK3 degrader-1 TMC-353121

TMC-353121

Smiles: O=C1NC2C=CC(Cl)=CC=2C(=C1C(=O)/C=C/C1C=NC=C(F)C=1)C1C=CC=CC=1

Smiles: CCOC1C=CC(CC2=CC(=CC=C2Cl)[C@@]23O[C@](CO2)(CO)[C@@H](O)[C@H](O)[C@H]3O)=CC=1

[O-]C(=O)CC[C@H](O)C([O-])=O

DM4 TAC SGK3 degrader-1 TMC-353121DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody drug conjugate. Product information CAS Number: 796073 69 3 Molecular Weight: 780. 37 Formula: C38H54ClN3O10S Chemical Name: (1S,2R,3S,5S,6S,20R,21S) 11 chloro 21 hydroxy 12,20 dimethoxy 2,5,9,16 tetramethyl 8,23 dioxo 4,24 dioxa 9,22 diazatetracyclo[19. 3. 1. 1,. 0,]hexacosa 10(26),11,13,16,18 pentaen 6 yl (2S) 2 (N,4 dimethyl 4