ATR inhibitor 2 oxamide Tromethamine is a small molecular tripeptide

is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo

Fmoc-Gln(Trt)-Thr(psi(Me

EBI-2511 displays a dose-dependent inhibition on the tumor growth

CAS Number: 651729-53-2

ATR inhibitor 2 oxamide Tromethamine is a small molecular tripeptideATR inhibitor 2 is an ATP competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. ATR inhibitor 2 potently inhibits ATR driven phosphorylated checkpoint kinase 1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity. Product information CAS Number: 1613191 99 3 Molecular Weight: 541. 55 Formula: C25H29F2N9O3 Chemical Name: 2 amino 6 fluoro N (5 fluoro 4 {4 [4 (oxetan 3 yl)piperazine 1 carbonyl]piperidin 1 yl}pyridin 3