4-Methylhistamine dihydrochloride Catalog No.:M22257-C 30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37

30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37

InChiKey: ZIJGVXBDFVHKQP-IHLOFXLRSA-N

FC1C=CC(=CC=1)C(C1C=CC(F)=CC=1)N1CCN(C/C=C/C2C=CC=CC=2)CC1

InChi: InChI=1S/C17H17N3O3S/c1-10-5-4-6-18-15(10)9-24(22)17-19-13-7-11(2)12(16(21)23-3)8-14(13)20-17/h4-8H

4-Methylhistamine dihydrochloride Catalog No.:M22257-C 30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(374 Methylhistamine dihydrochloride (or 4 methylhistamine) is a selective agonist of H4 receptor with a pEC50 value of 7. 40. 1 (=1) . In the chemotaxis of mast cells and leukocytes to sites of inflammation, the histamine H4 receptor (H4R) is involved . In transfected cells, 4 methylhistamine bound to hH4R with the highest affinity, compared to the binding to other histamine receptors. The interaction between 4 methylhistamine and hH4R showed a higher