TWS119 Size:10mg solid This sensitization of tumor cell

This sensitization of tumor cell lines with AKT-IN-VIII is not limited to LnCaP cells as similar apoptosis induction is observed in HT29

Pulmonary actions of LY255283

QDx21) in a dose-dependent manner and causes tumor regression at 100 mg/kg in H146 xenograft model

Formula: C18H15ClN6OS2

TWS119 Size:10mg solid This sensitization of tumor cellTWS 119 is a potent and selective inhibitor of glycogen synthase kinase 3 (IC50 = 30 nM). TWS119 could activate Wnt catenin pathway and up regulate the expression of CD62L in a dose dependent manner, but it decreased the expression of CD107a. Glycogen synthase kinase (GSK) 3, a constitutively active serine threonine kinase, acts as a key regulator of major signaling pathways, including the Wnt, Hedgehog, and Notch pathways. Product information CAS