Palbociclib-propargyl 314entane-1 5-diamine dihydrochloride 5-bis(trifluoromethyl)phenyl]formamido}oxy)-N-(4-chlorophenyl)propanamide

5-bis(trifluoromethyl)phenyl]formamido}oxy)-N-(4-chlorophenyl)propanamide

DRF-1042 treatment shows less mylosupression that supports the possibility of protracted dose schedule in both experimental and clinical studies

yGsy2p-IN-H23 is a potent and first-in-class inhibitor for yeast glycogen synthase 2 (yGsy2p) with an IC50 of 875 µM for human glycogen synthase 1 (hGYS1)

High affinity and highly potent activator of hM3Dq and hM4Di DREADDs (Ki values are 1

Palbociclib-propargyl 314entane-1 5-diamine dihydrochloride 5-bis(trifluoromethyl)phenyl]formamido}oxy)-N-(4-chlorophenyl)propanamidePalbociclib propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP 10. CP 10 shows a DC50 of 2. 1 nM for CDK6. Product information CAS Number: 2366269 23 8 Molecular Weight: 485. 58 Formula: C27H31N7O2 Chemical Name: 6 acetyl 8 cyclopentyl 5 methyl 2 ({5 [4 (prop 2 yn 1 yl)piperazin 1 yl]pyridin 2 yl}amino) 7H,8H pyrido[2,3 d]pyrimidin 7 one Smiles: