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It can enhance survival of human embryonic stem cells (hESCs) or iPSCs after single cell dissociation by trypsin
or the 2OG oxygenase FIH
Antagonism of the P2X3 receptor is one of the potential therapeutic strategies for the management of neuropathic pain because P2X3 receptors are predominantly localized on small to medium diameter C- and Aδ-fiber primary afferent neurons
Dumitras S
RO-9187 1470 (methanesulfonate) It can enhance survival ofRO 9187 is a potent inhibitor of HCV virus replication in the replicon system (IC(50) = 171 + 12 nM; CC(50) >1 mM). RO 9187 is an excellent substrate for deoxycytidine kinase and is phosphorylated with efficiencies up to 3 fold higher than deoxycytidine. RO 9187 is a new class of antiviral nucleosides with promising preclinical properties as potential medicines for the treatment of HCV infection. Product information CAS Number: 876708 03 1 Molecular