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Dimitris Stellas
10 μM E1R does not displace the radioligand
InChiKey: BKCJZNIZRWYHBN-UHFFFAOYSA-N
3R)-1-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-3-methyl-2-(methylsulfonyl)-2
erbB-2 u) Phosphoramidite Dimitris StellaserbB 2 is a transmembrane, tyrosine kinase (TK) receptor whose overexpression is associated with adverse prognosis in breast cancer1. The human epidermal growth factor receptor (erbB 2) is a transmembrane receptor that is overexpressed in 15%25% of breast cancers. erbB 2 overactivity is associated with adverse biological characteristics and poor clinical outcomes1. Overexpression of erbB2 in cell lines leads to transformation in the absence of a
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