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JANEX-1 - CAS# 202475-60-3 ns) ML216 displays low micromolar potency

SKU: 67627486555

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Description

ML216 displays low micromolar potency and selectivity over related helicases

Formula: C19H14N2O4

InChi: InChI=1S/C31H34N4O2/c1-3-34(2)31(37)24-14-17-26-27(20-24)33-30(36)28(26)29(23-10-6-4-7-11-23)32-25-15-12-22(13-16-25)21-35-18-8-5-9-19-35/h4

1374356-45-2

JANEX-1 - CAS# 202475-60-3 ns) ML216 displays low micromolar potencyWHI P131, also known as Janex 1, is a potent and selective Janus kinase 3 inhibitor with an IC50 value of 78 M. WHI P131 inhibits human glioblastoma cell adhesion and invasion. WHI P131 prevents graft versus host disease but spares the graft versus leukemia function of the bone marrow allografts in a murine bone marrow transplantation model. Product information CAS Number: 202475 60 3 Molecular Weight: 297. 31 Formula: C16H15N3O3 Synonym: WHI P131

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