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67±22 and 32±10% in placebo
although has low Mcl-1 levels
Formula: C22H26O7
N-dimethyl-2-oxoacetamide hydrochloride
JPH203 Dihydrochloride inase inhibitors 1 67±22 and 32±10% in placeboJPH203 Dihydrochloride is a tyrosine analog, acts as a selective inhibitor of L type amino acid transporter 1 (LAT1), and is used in cancer research. JPH203 Dihydrochloride is a selective inhibitor of LAT1. JPH203 (KYT 0353) inhibits 14C leucine uptake in S2 hLAT1 and HT 29 cells, with IC50s of 0. 14 uM and 0. 06 uM. JPH203 (3 1000 uM) exhibits concentration dependent inhibitory effects on S2 hLAT1 cell growth with an IC50 of 16. 4 uM. JPH203 also
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