CONC(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M17725_1634726763.gif?v=1634726764)
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Smiles: OC[C@@H](O)CONC(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F
29 nM and 13 nM
5-bis(trifluoromethyl)phenyl]-2-(H)methyl-N-methyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl](H)propanamide
InChiKey: DSZOEVVLZMNAEH-BXUJZNQYSA-N
BPN-15606 besylate xin G2 Smiles: OC[C@@H](O)CONC(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1FBPN 15606 besylate is a highly potent, orally active secretase modulator (GSM), attenuates the production of A42 and A40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN 15606 besylate lowers A42 and A40 levels in the central nervous system of rats and mice. BPN 15606 besylate has acceptable PK PD properties, including bioavailability, half life, and clearance. Product information Molecular Weight: 576. 64 Formula: