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Chemical Name: 2-{[(1R)-1-[7-methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1
DCC-2618 targets and binds to both wild-type and mutant forms of KIT and PDGFRa specifically at their switch pocket binding sites
with aclculated Ki of 0
SQ109 showed activity against both drug susceptible and Multi-drug-resistant tuberculosis bacteria
EGFR mutant-IN-1 Catalog No.:M17489-C Chemical Name: 2-{[(1R)-1-[7-methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1EGFR mutant IN 1, a 5 methylpyrimidopyridone derivative, is a potent and selective EGFRL858R T790M C797S mutant inhibitor with an IC50 of 27. 5 nM, while being a significantly less potent for EGFRWT (IC50 >1. 0 M). Product information Molecular Weight: 632. 17 Formula: C34H39ClFN7O2 Chemical Name: (R) 6 (2 chloro 3 fluorophenyl) 5 methyl 2 ((3 methyl 4 (4 methylpiperazin 1 yl)phenyl)amino) 8 (1 propionylpiperidin 3 yl)pyrido[2, 3 d]pyrimidin 7(8H) one
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