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AY 77 is a potent PAR2 biased agonist
Solubility: DMSO : ≥ 160 mg/mL (483
ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11
1'-biphenyl]-4-yl}ethoxy)pyrimidin-4-yl]phenyl}propanoic acid
Cathepsin G Inhibitor I 16895 AY 77 is a potentIC50: 53 nM Cathepsin G (EC 3. 4. 21. 20, chymotrypsin like proteinase, neutral proteinase) is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. Cathepsin G Inhibitor I is a potent, selective, reversible, competitive, non peptide inhibitor of cathepsin G. In vitro: Cathepsin G Inhibitor I shows reversible, competitive inhibition with IC50 and Ki values of 53 12 (N = 10) and 63 14 nM (N = 5),
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