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INT-777 is a semisynthetic bile acid that acts as an agonist of TGR5 (EC50 = 0
The inhibition of CDKs results in cell cycle arrest
Formula: C15H14ClN3O4S
Inhibition of TNKS1/2 poly(ADP-ribosyl)ation activity by JW55 led to stabilization of AXIN2
Loteprednol Etabonate Size:Solid 2 mg INT-777 is a semisynthetic bileThe compound is an ophthalmic corticosteroid, and categorized as an anti inflammatory. Loteprednol Etabonate is the esther of Loteprednol. This results in an induction of the synthesis of certain anti inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Marketed by Bausch and Lomb as Lotemax in the U. S., ocular applications for this drug include the treatment of inflammation of the eye due to allergies, as well as