Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death
cytotoxic to human monocytic leukemic cell lines
Prolonged stimulation of GPR40/FFA1 by TAK-875 does not cause pancreatic β Cell dysfunction or induction of apoptosis
NCCOC1C=C(N=C(C=1)C(=O)NC1=CC(OCCN)=C2C=CC=CC2=N1)C(=O)NC1=CC(OCCN)=C2C=CC=CC2=N1
DuP-697 rphostin A9 Erastin produces non-apoptotic tumor cellDuP 697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX 2 inhibitor (IC50 of 10 nM and 800 nM for human COX 2 and COX 1, respectively). DuP 697 exerts antiproliferative (IC50 of 42. 8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP 697 inhibits prostaglandin synthesis and has anti inflammatory, anticancer and antipyretic effects. Product information CAS Number: