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GSK189254 (0
PNU-152243
InChi: InChI=1S/2C21H29N6O5P
CAS Number: 1957236-22-4
(S)-WAY 100135 dihydrochloride thacholine chloride GSK189254 (0(S) WAY 100135 dihydrochloride is a potent and selective antagonist of 5 HT1A receptor with IC50 value of 15 nM. The 5 HT1A receptor is a G protein coupled receptor for endogenous neurotransmitter serotonin (5 HT) and mediates inhibitory neurotransmission. (S) WAY 100135 dihydrochloride is a potent and selective somatodendritic and postsynaptic 5 HT1A receptors antagonist. (+ ) WAY100135 inhibited 5 HT1A receptor in the rat hippocampal with IC50 value
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