![Pafuramidine - anti-parasitic agent. CAS# 186953-56-0 imopan dihydrate Smiles: CC1=CC(=CC(C)=C1)[C@@H]1CCCN1CC1C=CC(=CC=1)OC1=CC=C(C=C1F)C(N)=O](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M10327_1621561702.gif?v=1741822255)
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Smiles: CC1=CC(=CC(C)=C1)[C@@H]1CCCN1CC1C=CC(=CC=1)OC1=CC=C(C=C1F)C(N)=O
InChiKey: CWPKTBMRVATCBL-UHFFFAOYSA-N
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InChi: InChI=1S/C30H25F10NO3/c1-14(2)22-11-23(25(43-4)12-24(22)31)21-6-5-18(28(32
Pafuramidine - anti-parasitic agent. CAS# 186953-56-0 imopan dihydrate Smiles: CC1=CC(=CC(C)=C1)[C@@H]1CCCN1CC1C=CC(=CC=1)OC1=CC=C(C=C1F)C(N)=OPafuramidine, CAS NO. 186953 56 0, also known as DB289, is an orally bioavailable prodrug of furamidine (DB75) which was developed for the treatment of human African trypanosomiasis. Pafuramidine is less toxic than previous diamidines such as pentamidine. To date, human trials suggest that pafuramidine is well tolerated overall and has clinical activity against Pneumocystis pneumonia. DB289 is a promising new antimalarial compound that could become an