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(2014) Leukemia
3-d]pyrimidin-2-yl)methyl)acetamide
selective and orally bioavailable GPR39 agonist with an EC50 ~0
Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons
Crenolanib - CAS# 670220-88-9 60170 (2014) LeukemiaCrenolanib, CAS No. 670220 88 9, is a potent and selective inhibitor of PDGFR , FLT3 with Kd of 2. 1 nM 3. 2 nM, 0. 74 nM, respectively, sensitive to D842V mutation not V561D mutation, and > 100 fold more selective for PDGFR than c Kit, VEGFR 2, TIE 2, FGFR 2, EGFR, erbB2, and Src. Product information CAS Number: 670220 88 9 Molecular Weight: 443. 54 Formula: C26H29N5O2 Synonym: CP 868596 RO 002 Chemical Name: 1 (2 (5 ((3 methyloxetan 3 yl)methoxy) 1H