MID-1 O-isobutyryl-12-O-acetyltenacigenin B InChi: InChI=1S/C43H46N10O6/c1-5-53-34(20-30(50-53)25-13-14-25)46-39-37-27-19-33(58-4)28(36-22(2)51-59-23(36)3)18-31(27)45-38(37)48-40(49-39)42(56)44-17-8-6-7-10-24-11-9-12-26-29(24)21-52(43(26)57)32-15-16-35(54)47-41(32)55/h9

Name: MID-1 O-isobutyryl-12-O-acetyltenacigenin B InChi: InChI=1S/C43H46N10O6/c1-5-53-34(20-30(50-53)25-13-14-25)46-39-37-27-19-33(58-4)28(36-22(2)51-59-23(36)3)18-31(27)45-38(37)48-40(49-39)42(56)44-17-8-6-7-10-24-11-9-12-26-29(24)21-52(43(26)57)32-15-16-35(54)47-41(32)55/h9
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Description

InChi: InChI=1S/C43H46N10O6/c1-5-53-34(20-30(50-53)25-13-14-25)46-39-37-27-19-33(58-4)28(36-22(2)51-59-23(36)3)18-31(27)45-38(37)48-40(49-39)42(56)44-17-8-6-7-10-24-11-9-12-26-29(24)21-52(43(26)57)32-15-16-35(54)47-41(32)55/h9

24-96 hours

brown adipose tissue

after day 7

MID-1 O-isobutyryl-12-O-acetyltenacigenin B InChi: InChI=1S/C43H46N10O6/c1-5-53-34(20-30(50-53)25-13-14-25)46-39-37-27-19-33(58-4)28(36-22(2)51-59-23(36)3)18-31(27)45-38(37)48-40(49-39)42(56)44-17-8-6-7-10-24-11-9-12-26-29(24)21-52(43(26)57)32-15-16-35(54)47-41(32)55/h9MID 1 is a disruptor of MG53 IRS 1 (Mitsugumin 53 insulin receptor substrate 1) interaction. MID 1 disrupts molecular association of MG53 with IRS 1 and abolishes MG53 induced IRS 1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS 1 expression level and increased insulin signaling and glucose uptake. Product information CAS Number: 312608 54 1 Molecular Weight: 293. 30 Formula: C12H11N3O4S Chemical Name: 4 ethoxy N (5 nitro

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