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KB02-SLF Catalog No.:M15097-2 a novel proapoptotic agent

SKU: 54594065990

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Description

a novel proapoptotic agent

is a potassium channel activator

Chemical Name: (S)-6-(2-(4-cyanophenyl)-2-hydroxy-2-(1-methyl-1H-imidazol-5-yl)ethoxy)-4'-(trifluoromethoxy)-[1

and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM

KB02-SLF Catalog No.:M15097-2 a novel proapoptotic agentKB02 SLF is a PROTAC based nuclear FKBP12 degrader (molecular glue). KB02 SLF promotes nuclear FKBP12 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02 SLF. Product information CAS Number: 2384184 40 9 Molecular Weight: 949. 52 Formula: C50H65ClN4O12 Chemical Name: (1R) 1 [3 (3 {2 [2 (2 {[1 (2

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