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UK-92480 increases connexin 40 in smooth muscle cells through activation of BMP pathways in pulmonary arterial hypertension
Ki16425 reduces the LPA-induced activation of p42/p44 mitogen activated protein kinase (MAPK)
PubMed PMID: 9020426
1038/s41598-017-08711-6
NVP-BGJ398 phosphate Catalog No.:M9579-10 UK-92480 increases connexin 40 inInfigratinib, also known as, BGJ398 or NVP BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell