KPT-185 Size:Solid 10 mg CC(C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1C1NC(=CN=1)C1C=CC(=CC=1)C1C=CC(=CC=1)C1=CN=C(N1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

CC(C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1C1NC(=CN=1)C1C=CC(=CC=1)C1C=CC(=CC=1)C1=CN=C(N1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

Aticaprant (CERC-501) produces antidepressant-like effects in the mouse forced swim test and enhances the effects of imipramine and citalopram

5-dihydro-1H-1

Stejskal A

KPT-185 Size:Solid 10 mg CC(C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1C1NC(=CN=1)C1C=CC(=CC=1)C1C=CC(=CC=1)C1=CN=C(N1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)CKPT 185 is a selective and irreversible inhibitor of chromosome maintenance protein 1 (CRM1). CRM is an important nuclear protein export receptor. Blocking CRM1 mediated nuclear export can result in the suppression of tumors. Product information CAS Number: 1333151 73 7 Molecular Weight: 355. 31 Formula: C16H16F3N3O3 Chemical Name: propan 2 yl (2Z) 3 {3 [3 methoxy 5 (trifluoromethyl)phenyl] 1H 1,2,4 triazol 1 yl}prop 2 enoate Smiles: