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PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1
16-7+/t17-
PubMed PMID: 26392512
24)/b15-13+
(±)-AMG 487 CS-010759 PD-1/PD-L1-IN 5 is a PD-1/PD-L1() AMG 487 is a racemate of AMG 487. AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8. 0 and 8. 2 nM, respectively. Product information CAS Number: 947536 03 0 Molecular Weight: 603. 59 Formula: C32H28F3N5O4 Chemical Name: N {1 [3 (4 ethoxyphenyl) 4 oxo 3H,4H pyrido[2,3 d]pyrimidin 2 yl]ethyl} N [(pyridin 3 yl)methyl] 2 [4
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