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AS-604850 blocks PKB phosphorylation induced by MCP-1 and has little or no effect after stimulation with CSF-1 in in primary monocytes from Pik3cg+/+ or Pik3cg–/– mice
InChi: InChI=1S/C9H23NO7P2/c1-3-4-5-7-10(2)8-6-9(11
Smiles: CC(C)[C@@H](C)[C@@H](O)[C@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3COC(=O)[C@H]4C[C@H](O)[C@H](O)C[C@]4(C)[C@H]3CC[C@@]21C
8-diazacycloundecan-10-yl)amino)-1-oxohexan-2-yl)carbamoyl)-1-((4R
IDO-IN-3 60002 AS-604850 blocks PKB phosphorylation inducedIDO IN 3 is a potent indoleamine 2,3 dioxygenase (IDO) inhibitor with an IC50 of 290 nM. Product information CAS Number: 2070018 30 1 Molecular Weight: 359. 15 Formula: C11H12BrFN6O2 Chemical Name: (E) 4 [(2 aminoethyl)amino] N (3 bromo 4 fluorophenyl) N' hydroxy 1,2,5 oxadiazole 3 carboximidamide Smiles: NCCNC1=NON=C1 C( NC1C=CC(F)=C(Br)C=1)=N\O InChiKey: DAPNMIADTFAXEG UHFFFAOYSA N InChi: InChI=1S C11H12BrFN6O2 c12 7 5 6(1 2 8(7)13)16 11(17 20)9