Pay in 4 interest-free payments of $28.50 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
InChi: InChI=1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16
Formula: C29H33NO5
CAS Number: 170729-80-3
Formula: C23H30Cl3N5O3
CP-466722 Size:Solid 10 mg InChi: InChI=1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16CP 466722 is an ATM inhibitor. CP466722 inhibited cellular ATM dependent phosphorylation events and disruption of ATM function resulted in characteristic cell cycle checkpoint defects. Inhibition of cellular ATM kinase activity was rapidly and completely reversed by removing CP466722. Interestingly, clonogenic survival assays showed that transient inhibition of ATM is sufficient to sensitize cells to IR and suggests that therapeutic radiosensitization
US$ 1300.00
US$ 1000.00