Tpl2 Kinase Inhibitor 1 - CAS# 871307-18-5 Size:2mg solid Smiles: NC1=NC(=CS1)/C(=C/CC(O)=O)/C(=O)N[C@H]1[C@H]2SCC=C(C(O)=O)N2C1=O

Smiles: NC1=NC(=CS1)/C(=C/CC(O)=O)/C(=O)N[C@H]1[C@H]2SCC=C(C(O)=O)N2C1=O

Solubility: DMSO : 50 mg/mL (128

exerting a hepatoprotective effect against alpha-fas-induced liver injury in a mouse model

and proinflammatory cytokine production

Tpl2 Kinase Inhibitor 1 - CAS# 871307-18-5 Size:2mg solid Smiles: NC1=NC(=CS1)/C(=C/CC(O)=O)/C(=O)N[C@H]1[C@H]2SCC=C(C(O)=O)N2C1=OTpl2 Kinase Inhibitor 1 (Compound 1) is a potent and selective Tpl2 (COT kinase, MAP3K8) inhibitor, plays an important role in the regulation of the inflammatory response and the progression of some cancers. Product information CAS Number: 871307 18 5 Molecular Weight: 404. 83 Formula: C21H14ClFN6 Chemical Name: 4 [(3 chloro 4 fluorophenyl)amino] 6 {[(pyridin 3 yl)methyl]amino} 1, 7 naphthyridine 3 carbonitrile Smiles: