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GSK3368715 (EPZ019997) significantly effects on the growth of BxPC3 xenografts at all doses tested
Formula: C17H21N3O6S2
With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS
In the human U937 monocytic cell line or peripheral blood mononuclear cells
DPNI-caged-GABA 724F-05180999 GSK3368715 (EPZ019997) significantly effects onIC50: N A DPNI GABA, also known as Nitroindoline caged GABA, has similar photochemical properties with MNI glutamate, including the same quantum yield (0. 085), highly water soluble, exhibitting fast photorelease that is efficient at near UV and 405 nm wavelengths. In vitro: Under the condition of retaining the advantages of nitroindoline cages, DPNI GABA were modified to minimize the pharmacological interference commonly found with caged GABA
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