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Desmethyl cariprazine Catalog No.:M27778-C 52(4):1246-1254

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Description

52(4):1246-1254

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

Strong electron density is observed for IT1t in the binding cavity of both subunits of the CXCR4 homodimer

InChi: InChI=1S/C28H26F3N7O2/c1-15-7-9-19(12-22(15)32)36-27-34-14-21(24(33-3)38-27)26(40)37-23-13-20(10-8-16(23)2)35-25(39)17-5-4-6-18(11-17)28(29

Desmethyl cariprazine Catalog No.:M27778-C 52(4):1246-1254Desmethyl cariprazine is an active metabolite of Cariprazine. Cariprazine, an antipsychotic drug candidate, exhibits high affinity for the D3 (Ki=0. 085 nM) and D2 (0. 49 nM) receptors, and moderate affinity for the 5 HT1A receptor (2. 6 nM). Product information CAS Number: 839712 15 1 Molecular Weight: 413. 38 Formula: C20H30Cl2N4O Chemical Name: 1 (4 {2 [4 (2,3 dichlorophenyl)piperazin 1 yl]ethyl}cyclohexyl) 3 methylurea Smiles:

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